Among eligible patients, there is substantial variation in the risk of dying of lung cancer.

Different patients need different conversations.

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A screening decision for Mr. Roberts is more preference sensitive. His lower risk of dying from lung cancer means there is a fine balance between benefit and harm with LDCT screening.

On the other hand, Mrs. Lee is considered a high benefit person. She has a much higher lung cancer risk and can expect a mortality benefit with LDCT screening that is large compared to the harms.